GE Liu, Y Hou, JM Robl, Y Kuroiwa… - Genome Integrity, 2011 - ncbi.nlm.nih.gov ... However, because primary somatic cells have limited life span and inevitably become senescent following DNA transfection and selection in cell culture, it is impossible to perform any further genetic modifications in these cells. ... -
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D Jones - The Yale Journal of Biology and Medicine, 2011 - ncbi.nlm.nih.gov Genetic engineering is the process of modifying an organism's genetic composition by adding foreign genes to produce desired traits or evaluate function. Dr. Jon W. Gordon and Sterling Professor Emeritus at Yale Dr. Frank H. Ruddle were pioneers in mammalian gene transfer ... -
B Brand, A Hartmann, D Repsilber… - Genetics Selection …, 2011 - gsejournal.org During the past ten years many quantitative trait loci (QTL) affecting mastitis incidence and mastitis related traits like somatic cell score (SCS) were identified in cattle. However, little is known about the molecular architecture of QTL affecting mastitis susceptibility and the underlying ... -
R Rupp, V Clément, A Piacere… - Journal of Dairy …, 2011 - Elsevier Goat milk somatic cell counts have been collected for several years in France by the national milk recording organization. Information is used for health management, because repeatedly elevated somatic cell counts are a good indirect predictor of intramammary infection. ...