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V Najfeld, N Wisch, J Mascarenhas, L Issa… - Cancer Genetics, 2011 - Elsevier
A 65-year-old patient with a high hemoglobin and hematocrit was treated for 14 months with
therapeutic phlebotomy when cytogenetics of bone marrow revealed 100% cells with the Ph
chromosome and 45% of the Ph+ cells contained trisomy 8. Treatment with tyrosine ...
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JM Hagenkord, Z Gatalica, E Jonasch… - Cancer Genetics, 2011 - Elsevier
Kidney and upper urinary tract cancers account for approximately 54,000 cases every year in
the United States, and represent about 3.7% of adult malignancies, with more than 13,000 annual
deaths. Classification of renal tumors is typically based on histomorphologic ...

I Cima, R Schiess, P Wild, M Kaelin… - Proceedings of the …, 2011 - National Acad 必威最新网址ences
A key barrier to the realization of personalized medicine for cancer is the identification of
biomarkers. Here we describe a two-stage strategy for the discovery of serum biomarker signatures
corresponding to specific cancer-causing mutations and its application to prostate cancer ( ...
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C Eng - JAMA: The Journal of the American Medical …, 2011 - Am Med Assoc
Close inspection reveals that this is not the typical cancer genetics textbook, which would correctly
focus on the high-penetrance mendelian genes associated with hereditary breast and ovarian
cancer syndrome, BRCA1 and BRCA2, and with Lynch syndrome (hereditary ...

KR Blazer, DJ MacDonald, JO Culver… - Genetics in …, 2011 - journals.lww.com
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